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Some synthesized compounds have already been famous to get 100 times far more potent than the common THC located in marijuana. The stronger binding with the artificial chemicals to the THC receptor web-sites from the Mind may produce the extreme anxiety and paranoia that have already been reported in a few users.

Marijuana might be smoked like a cigarette (identified as a joint or simply a nail) or inside a glass pipe or possibly a drinking water pipe ("bong"). It could be smoked in "blunts", which are cigars that have already been emptied of tobacco and refilled with marijuana, typically together with An additional drug, including crack.

Companies make an effort to evade these legal constraints by substituting distinct chemicals of their mixtures, when the DEA proceeds to observe and update the list of banned cannabinoid derivatives.one

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There have been reports that Spice or K2 can be laced with other illicit substances, like fentanyl, which can swiftly produce respiratory despair and death.

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